


Nuclear medicine
Nuclear medicine
Radioactive substances are used for examining the treating diseases.
Some radioactive materials, such as technetium-99m and iodine-123, are used for diagnostic purposes. The radioactive medicinal substance used for diagnostic purposes is injected into the bloodstream, administered orally or the patient inhales it as an aerosol. The radioactive agent attaches itself specifically to the organ being examined. The accumulation of radioactivity in the organ and body can be monitored with a gamma camera. This provides information on the organ being examined. These examinations are known as isotopic studies.
Approximately 50,000 isotopic studies are performed annually in Finland, most of them on the skeletal system. The lungs, kidneys, vascular system cardiovascular system and thyroid gland can also be examined, among others. One isotopic study results in an average exposure of 4.2 mSv to the patient. All isotopic studies result in an average dose of approximately 0.04 mSv per Finn.
Radioactive iodine-131 is used for treating hyperthyroidism and thyroid cancer. Radioiodine attaches itself specifically to the thyroid gland and destroys hyperactive thyroid gland tissue or tumour. The radiation doses caused to patients from these isotopic treatments are considerably higher than the doses from isotopic studies.
Radiation doses of comparison levels of isotopic studies
Isotopic study |
Radionuclide |
Compound or chemical form |
Comparison level (MBq) |
Effective dose (mSv) |
---|---|---|---|---|
Skeletal system and soft tissue |
||||
Gamma imaging of the skeletal system |
99mTc |
Phosphates or phosphonates |
670 |
3.8 |
Gamma imaging of infection site |
99mTc |
Leukocytes (HMPAO) |
300 |
3.3 |
Respiratory system |
||||
Gamma imaging of pulmonary perfusion |
99mTc |
MAA |
150 |
1.7 |
Urogenital system |
||||
Gamma imaging of renal function |
99mTc |
MAG3 |
100 |
0.7 |
Cardiovascular system |
||||
Myocardial perfusion SPECT |
201Tl |
Ion |
100 |
22 |
Myocardial perfusion SPECT |
99mTc |
MIBI (rest + stress) |
1000 1) |
8.5 |
|
|
|
1200 2) |
10.1 |
Myocardial perfusion SPECT |
99mTc |
Tetrofosmin (rest + stress) |
1000 1) |
7.3 |
|
|
|
1200 2) |
8.8 |
Gamma imaging of cardiac pump function (at equilibrium) |
99mTc |
Erythrocytes |
750 |
5.3 |
Nervous system |
||||
Dopamine transporter SPECT imaging |
123I |
β-CIT |
180 |
9.0 |
|
123I |
FP-CIT |
180 |
4.2 |
Endocrinologic isotope studies |
||||
Gamma imaging of thyroid metastases (after ablation) |
131I |
Iodide |
185 |
11.3 |
Gamma imaging of parathyroid gland |
99mTc |
MIBI |
740 |
6.7 |
PET studies |
|
|
|
|
Imaging of tumours |
18F |
FDG |
2803) |
5.3 |
Imaging of tumours |
18F |
FDG |
3704) |
7.0 |
1) Total activity administered to the patient when the stress and rest phases are performed within 24 hours of each other.
2) Total activity administered to the patient when the stress and rest phases are performed on different days.
3) 3D imaging and time-of-flight technology in use
4) 2D imaging in use
Contact
Contact
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Tel. +358 975 988 542